THE BASIC PRINCIPLES OF 1% PENTOBARBITAL SODIUM

Phenobarbital has actually been shown to shorten the 50 %-lifetime of doxycycline for as long as 2 months soon after barbiturate therapy is discontinued. This mechanism is probably through the induction of hepatic microsomal enzymes that metabolize the antibiotic.The outcome of barbiturates over the metabolism of phenytoin seems to get variable. So